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Harpur Professor's Small Pump Has Big Potential

A low power, electrically driven pumping device developed by a Harpur College professor and his team of undergraduates, graduate students, and a post-doctoral researcher could significantly enhance the quality of life for diabetics around the world in the next three to four years.

Zhong hopes his pumpless pump will have many applications.

CJ Zhong, assistant professor of Chemistry, is leading the effort on a low power, electrically driven pumping device that will be able to perform microfluidic analysis and potentially remain in the body, constantly measuring the need for insulin, and deliver precise amounts.

Zhong has dubbed it a "pumpless pump" because it lacks mechanical parts. A wire sends an electrical voltage to two immiscible fluids in a tiny column, which could be as small as the diameter of a hair. Applying opposite charges to each side of the column causes the fluids to oscillate, thereby simulating the action of a pump.

The pumping device will be the size of a computer chip, perhaps as small as an adult's fingernail. It is made of a detector, column filled with moving liquid, and an injector.

Here is how Zhong's "pumpless pump" can potentially help a diabetic: the detector, a tiny electrical wire, measures the body's insulin level. It responds by electrically charging the fluid in the column to make it move. The motion in the column triggers the injector to supply the patient with more insulin from an external source. The detector works constantly, eliminating the patient's need for regular blood tests. Because less time has passed between injections, insulin levels do not soar and surge as dramatically.

This tiny system works like a thermostat: it takes a small sample, analyzes it, and tells other components how to act in response.

Zhong's pumping device will be so small that doctors can insert it into the body, eliminating the need for round-the-clock tests and injections. It will be wireless, so the patient can wear a small battery pack to power it.

He stresses that this is not an "artificial pancreas," but one part of a system that could someday be just that.


Working on Zhong's team is part of a senior honors project for Laura Moussa `03.

Diabetics are not the only ones who will benefit from this tiny pumping device. Every small, closed environment can benefit from tiny equipment that requires little fuel and produces no waste.

"For example, there's the space shuttle," says Zhong, "If you want to analyze the water quality, you can take as little a sample as possible. If it's a long duration, the supply is going to run out and the astronauts have to make sure the water is drinkable."

He says the pumping device can also work via remote control, working where human hands can not -- or should not reach. "One of the labs we're working with on this project is interested in dealing with metal contaminants from nuclear waste," said Zhong. "Their current technology is to go in the field, take samples of contaminated soil, and analyze them back in the lab. What we want to do is make remote controllable portable chip devices that sit in the field."

Making lab machinery smaller and more efficient is one of Zhong's chief goals. He cites the computer as an example of something that has evolved from large and slow to small and fast. "Look at the computer," he says, "Twenty years ago, it was huge. Now it's tiny." He hopes to create what he calls a "lab on a chip," by shrinking down all of the machinery in a chemistry lab to the size of computer chips.

Smaller equipment uses fewer resources and creates less waste because less fuel is necessary. (Consider the difference between a Mack Truck and a Volkswagen.) "Large equipment typically generates waste, said Zhong, "but if you use a miniature instrument, there's almost no waste." For instance, because his new pump is so small, it runs only on an electrical current supplied by a tiny battery. A conventional pump could require the power of a generator, which needs gasoline and emits toxic fumes as a byproduct.

His pumpless pump's advantage is its design. "Mechanical parts need maintenance and repair," explained Zhong. "This is basically a fluid pumping mechanism," in other words, an electrical current is creating a pumping motion by moving fluid through a channel. No need for lubrication, repairs, or spare parts. This system is practically weightless, especially compared to a conventional pump.

Right now, Zhong's invention is still in the prototype state, but this "pumpless pump" that is weightless, maintenance-free and implantable in the human body is not too far off. "We are not there yet, but this is going to take off very fast," he anticipates, perhaps three to four years. Not fast enough for diabetics who would gladly trade lancets and blood test strips for a tiny internal sensor attached to an insulin pump. For something so miniature, it could be a huge lifesaver.

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BU Creates First MS in Biomedical Anthropology

As SARS and other new diseases cross geographic boundaries with increasing rapidity, the need for Binghamton University's new master of science in biomedical anthropology becomes even more apparent.

Who's Who on the Faculty

Behind the hands-on aspect of the degree is an all-star lineup of the best Harpur College faculty from across several disciplines. Joining Ralph Garruto, whose specialties include the study of disease and aging, are:

Gary D. James, research professor of nursing and of anthropology, adjunct professor of psychology, and director of the Institute for Primary and Preventive Health Care.

Michael A. Little, distinguished professor of anthropology, whose studies of environmental biology, growth, reproduction, and adaptability have taken him through the Andes and East Africa.

J. Koji Lum, associate professor of anthropology, researches molecular anthropology, forensic genetics and malaria in Micronesia, Melanesia and Africa.

D. Andrew Merriweather, associate professor of anthropology, will join the faculty in August 2003. He studies ancient DNA and the genetics of populations throughout the Americas and the Pacific.

John Relethford, adjunct professor of anthropology, researches the evolution and genetics of modern humans, demography, and population genetics.

G. Philip Rightmire, distinguished professor of anthropology, has traveled throughout Africa and the Republic of Georgia, studying paleoanthropology, human evolution, and skeletal biology.

Dawnie Wolfe Steadman, assistant professor of anthropology, is a skeletal biologist who specializes in forensic anthropology, bioarchaeology and paleopathology.

David Sloan Wilson, professor of anthropology and biological sciences, researches genetics and culture, evolution, and integration of biology and the human social sciences.

The program, the first of its kind in the world, will offer a multi-disciplinary approach to the study of the transmission and spread of infections, cellular and molecular mechanisms of disease, and the interaction of biological and socio-cultural factors that shape health outcomes.


Prof. Garruto is overseeing the new M.S. in Biomedical Anthropology.

The 43-credit program, which requires an internship and a laboratory practicum, will admit 24 full-time and 6 part-time students from disciplines as diverse as nursing, anthropology, psychology, social work, biology and other health-related fields next fall. SUNY certified the program last fall.

"The degree program was in response to a University-wide call for proposals for applied, integrated master's-level programs that satisfy growing employment opportunities locally, statewide, nationally and internationally," said Ralph Garruto, research professor of anthropology and neuroscience, who oversees the program.

Binghamton's timing could not have been better. In the late 1990's, the National Academy of Sciences, and later the National Science Foundation, urged that graduate student training be strengthened to meet the needs of a modern and developing world. As a result, the NSF implemented its Integrative Graduate Education and Research Training.


Graduate students Michael Ryan and Julia Gaines evaluate x-rays for the presence of osteoarthritis in Chamorro patients from Guam.

Although BU's program in biomedical anthropology is not part of the NSF initiative, it is built upon that concept.

"Biomedical anthropology represents the interface between medicine and the behavioral and social sciences," said Garruto. "It is set up to give broad-based training across disciplinary boundaries, the interface between anthropology and biomedicine, bringing everything into a single academic framework."

Although biomedical anthropology is a specialization of biological anthropology, Garruto said students can specialize even further by taking electives in subjects such as evolutionary medicine, genetics, human growth and development, population dynamics and rural health.

Nine research facilities within BU will give students a broad spectrum of specialized, hands-on training. Within those are laboratories for forensic anthropology, forensic DNA identification, and paleoanthropology and skeletal biology.

Just as the professors come from several disciplines, so do the learning opportunities.

"One of the newest developments is a proposed clinical research core which would be shared by bioengineering, anthropology and nursing," said Garruto. "The core laboratories and clinical exam rooms will allow students in-depth, hands-on research and training across the lifespan in such areas as child growth and development, bone studies such as osteoporosis and osteoarthritis (with Ken McLeod of bioengineering), hypertension, cardiovascular disease and lifestyle research (with Gary James of nursing), as well as issues relevant to women's health, rural health and migrant health."

Garruto said with the recent hire of Professor J. Koji Lum, biomedical anthropology will soon gain both a molecular anthropology program and a forensic DNA identification lab.

"We want to gear the students in the program to become versatile professionals and, on completion of their program, have a tool kit that will allow them to move in a number of different employment directions," Garruto said.

Employment opportunities are likely to be with the World Health Organization, U.S. Department of Agriculture, Centers for Disease Control, National Institutes of Health, OSHA, N.Y. Center for Agricultural and Occupational Health, Peace Corps, World Bank, and institutions such as hospitals, county health departments, aging centers, and coroners' offices.

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Romano Lecture Offers Perspective on Globalism

About the Romano Lecture


Robert and Lucia Canon, Antoinette Romano and her son Richard `64, `65.

The Mario `69 and Antoinette Romano Lecture Series was endowed in 1984 by the couple as a tribute to Mario's years as a Harpur College student. Each year, their endowment sponsors a lecture given by esteemed speakers in economics, history, art history, and medicine.

Richard Romano (M.A. `64, Ph.D. `65), son of the late Mario Romano `69, said he and his family are glad to sponsor these lectures.  "We are happy Harpur College benefits from the modest endowment we've been able to create," he said, "A lecture series is an important 'extra' the University can do.  It enriches the intellectual environment."

Jeffrey G. Williamson, the Laird Bell Professor of Economics at Harvard University, presented the 2003 Mario and Antoinette Romano Lecture, "Going Global: A 500 Year Perspective" to an audience of nearly 50 faculty, students, and members of the Binghamton community on Thursday, April 24.  Williamson delivered a long-term, historical perspective on the influence of globalization on the quality of life since the era of Christopher Columbus.


Professor Williamson and Harpur College Dean Jean-Pierre Mileur

He began by asking the audience to consider the meaning of the word "globalization."  From an economics perspective, Williamson said it is anything that forces market integration, such as liberal policies, improved transportation, or more global-friendly institutions.  Travel seems to inspire commerce. "There was a big trade boom after Columbus's voyage in 1492," he explained.

The wealthy have always influenced trade, said Williamson, citing that historically, 10% of Europe's population consumed 90% of imported goods, such as spices and teas from Asia.  "The wealthy wanted exotic things," he said.  "Inequality caused trade."

However, Williams said over the last 20 years, world inequality has decreased because of growth in China and throughout Southeast Asia.  "Open economies grow faster," said Williamson.

He also contended that the third world is making great strides in the global economy by exporting consumer goods to developed nations.  "They're not exporting bananas anymore.  Chances are, if you buy a soccer ball today, it was made in Indonesia," he said, "The third world is in the industrial revolution game."

Williamson concluded that in spite of economic progress the third world still lags behind and wealthy nations should help those less fortunate. 

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Law Council Receptions Branch Out
by Rob de la Fuente `98


Allen Cohen `85 and Sheldon Goldfarb `73, the hosts of recent Harpur Law Council events.

The Harpur Law Council had two first-ever regional events this spring.  On March 18th we were on Long Island at Nixon Peabody, LLP in Garden City, NY.  While at Nixon Peabody partner Allen H. Cohen'85 was our most gracious host.  On April 2nd we had the pleasure of being in Greenwich, Connecticut at Greenwich Capital Markets, hosted by Sheldon I. Goldfarb'73.  Both events were a big success!

Over 50 law alumni, spanning a wide array of grad years, gathered to meet, greet, and network with their fellow attorneys.  While the evenings were filled with nostalgia and camaraderie, many attendees took the opportunity to exchange information in the hopes of enhancing future business contacts.

Both Cohen and Goldfarb welcomed their fellow alumni and spoke about the impact Harpur College had on their lives.  Jean-Pierre Mileur, Dean of Harpur College, provided an update on the state of the University mentioning the College's continued competitiveness and academic renown.  Dean Mileur asked those present to consider supporting Harpur College with a financial contribution noting that the generous support of its alumni would ensure the school's continued success.

Projects and programs sponsored by the Harpur Law Council were outlined, including the summer internships for pre-law undergraduates, and the online alumni law directory.  To view the directory, go to http://www.harpur.binghamton.edu/lawdirect/.  All alumni attorneys were encouraged to support these efforts and to reconnect with their alma mater.

Several alumni at the Long Island reception at Nixon Peabody LLP.

Jocelyn Nager `85, Rich Alpern `69, Dean Mileur, Mathew Paulose `95

Stacy Werner `91, Dean Mileur, Sheldon Goldfarb `73, John Cannavino `73

Beth Avery `87, Andrea Dulberg `82, Andrea Levine `92

The Harpur Law Council was formed in 1995 to serve the needs and interests of Binghamton University alumni attorneys and pre-law students. Its goal is to strengthen the university's mission and tradition of academic excellence. The Harpur Law Council advises the Harpur College Dean and the University Alumni Association on matters regarding academic issues and programs relevant to the legal profession. Through a comprehensive mix of volunteer opportunities and programs, the Harpur Law Council cultivates positive relationships among law alumni, students, and the campus community.

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Four to receive honorary degrees at Commencement


BU will award honorary doctorates to Sydney Pollack, Alan MacDiarmid, Dean Kamen and Mark Zurack `78

Binghamton University will award four honorary doctorates during Commencement ceremonies Sunday, May 18, at the Broome County Veterans Memorial Arena. The degree recipients will also give remarks during the ceremonies. Director Sydney Pollack and Nobel Prize-winning chemist Alan MacDiarmid will speak at the Harpur College of Arts and Sciences ceremony beginning at 9 a.m. Inventor Dean Kamen and investment banker and alumnus Mark Zurack ’78 will speak at the ceremony for the Graduate and professional schools beginning at 12:30 p.m. More...

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Foreign Language Honor Society Inducts New Members

Phi Sigma Iota, pictured above with administrators and faculty advisors, at Binghamton University is in its tenth year. Students of French, German, Spanish and Italian are eligible to join.

Binghamton University's Beta Omega chapter of Phi Sigma Iota International Foreign Language Honor Society inducted thirty-one new members on April 6, 2003.

At the ceremony, keynote speaker Paul Steidlmeier, associate professor of Management and director of Undergraduate Programs in the School of Management, stressed the importance of learning foreign languages.

He spoke of the challenges of learning to speak Mandarin while taking graduate courses in Taiwan and how learning a new language opened up his world to new experiences, new cultures, and new relationships.

Dora Polachek, visiting associate professor of Romance Languages and Literatures and faculty advisor to Phi Sigma Iota, congratulated the inductees and invited one student representing each of the modern languages taught at Harpur College to come to the podium and place a carnation in a vase, which served as a "symbolic candle lighting" for the new members' induction into the Honor Society.

Jean Quataert, professor of History, and Mary Lee Sullivan, visiting assistant professor of Romance Languages and Literatures, also spoke at the ceremony.

"The languages that you learn are a part of you and they can be activated and reactivated all of your life," said Quataert, "They're a gift you give yourself." She said with the right choice of words, "foreign languages can build bridges, even serious political divides."

Sullivan reiterated Quataert's point and encouraged everyone to travel abroad and make friends from different countries. "People who travel without knowing a foreign language are struck by the differences between others, but people who can converse in other languages see how similar we all are," she said.

Giselles Avevedo `03, a double major in Spanish Literature and Biology, was among the inductees and agreed wholeheartedly with all of the speeches. Having emigrated to the United States from the Dominican Republic in 1995, she knows firsthand how learning new languages brings people together. "Coming here helped me learn all about myself and appreciate my own culture more."

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Wine Tasting Event to Support the Arts

"Let Us Entertain You: The Art Supports the Arts," a benefit wine tasting will be held from 5-9 p.m. Wednesday, May 7, in the Anderson Center Reception Hall. Proceeds will go to the Harpur Fine Arts Internship Program, which places students with professional performing and visual arts companies and threatened by state cutbacks. The event will consist of a donated tasting, offered by several Finger Lakes wineries; elegant hors d'oeuvres and finger foods donated by Sodexho and the University; performances by students and faculty members; and auction of art and sports items including Broadway and New York Rangers tickets. Tickets at $25 ($40 per couple) are available at the Anderson Center box Office or by calling 777-2787.

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Harpur Friends & Family

In response to your much-appreciated feedback, the Harpur Hotline has developed a regular feature of alumni news. Please send us anything you want: publications, promotions, marriages, babies, graduations, retirements, etc. Many thanks to everyone who shared their stories! Here's what some of your fellow Harpur alumni and friends are doing:

Maria Mazziotti Gillan, director of the Creative Writing Program and author of numerous books, including her most recent "Italian Women in Black Dresses," will give a reading of her poetry at the Nutley Public Library in Nutley, NJ at 7:00p.m. on Monday, May 12. The public is invited to attend, but reservations for seating must be made beforehand by contacting the Nutley Public Library at 973-667-0405, or by writing to Nutley Public Library, 93 Booth Drive, Nutley New Jersey 07110.

Kudos to Donald Quataert, professor of history, who was recently named a Guggenheim Fellow by the John Simon Guggenheim Memorial Foundation. The fellowship will allow Quataert to continue researching the coal miners of the Ottoman Empire between 1829 and 1922.

Isidore Okpewho, professor of Africana studies, featured in the April 16 Harpur Hotline, also received a Guggenheim fellowship.


Congratulations to Leslie Gates, assistant professor of Sociology. The Friends of the Princeton University Women's Center recently awarded her their Women's Leadership Award for her commitment to serving women's special needs. Gates, who graduated from Princeton in 1990, now studies globalization, union power, and women's industrial work in Latin America.

1965: Sandra Koser Steingart is a psychologist with Baltimore County Public Schools, Towson, MD and is an expert on using the Internet for finding school psychology resources.  She is the creator of School Psychology Resources Online and recently wrote "The Web Connected School Psychologist."  Steingart is also webmaster of the Maryland School Psychologists' Association.  Her son, Daniel Steingart, graduated from Harpur College in 2001.

1972: Ann Prusinski is vice president of Stardust Dance Productions, which promotes "the ultimate in ballroom dance weekends."  She is an avid traveler and a former tour guide with Globus Gateway.  Prusinski has been an elected official since 1985 and is currently councilman for Fallsburg, NY.  She divides her time between New York City and the Catskills.  Prusinski wants to know if anyone remembers Harpur alumni Paul Geffner, Warren Lewis or Ron Wilson.

1977: Following graduation from Rutgers University School of Law, Wayne Greenfeder served as Law Clerk to the Honorable Morton I. Greenberg, now on the United States Court of Appeals for the Third Circuit.  He is a partner in the law firm of Kraemer, Burns, Mytelka, Lovell, and Kulka, P.A. in Springfield, N.J. and recently represented one of the plaintiffs in the high profile New Jersey Turnpike shooting case.  Greenfeder and his wife, Catherine, have one son and reside in Nutley, NJ.

1980: After graduating from Binghamton, Mark Weiss (MA, Chemistry) worked for nearly 17 years as a pharmaceutical chemist and in other positions for Lederle Laboratories, which eventually became Wyeth. In 1985, Weiss earned a Master's in Specialized Journalism from Polytechnic University and began freelance writing for chemical and pharmaceutical industry trade magazines as well as newsletters on dog and cat health. "Freelancing gave me a way to build a portfolio and gain a lot of writing experience and meet a lot of people, particularly those in the chemical and pharmaceutical industries," he recalls. Weiss has written and published over 150 bylined and ghost written articles and is now a senior technical and scientific writer for Purdue Pharma LP . He is also scheduled to give an oral presentation, "One Scientist at a Time: Integration of a Scientific and Technical Writing Department into Pharmaceutical R&D," at the 39th annual meeting of the Drug Information Association this summer. Weiss and his wife, Ilene, live in Congers, NY.

1980: Congratulations to Jorge L. Chinea (M.A. `83). Wayne State University recently promoted him to the rank of Associate Professor of History! Chinea previously earned a Ph.D. from the University of Minnesota. He has published several articles about Latin American history, including "Fissures in el Primer Piso: Racial Politics in Spanish Colonial Puerto Rico during its Pre-Plantation Era, c.1700-1800" (2002) in Caribbean Studies. Chinea was the founder and first director of the Latin American Music Department at WHRW-FM. He and his wife, Terri (Williams `83), have three children: Marcus, Mateo and Monica.

1987: After graduation, John Fracchia (M.B.A. `90) and Kerry Forrestal `86 (M.B.A. `92) operated a small advertising firm in Binghamton called "The Idea Mill." Fracchia recalls, "A horrendous economy and more ideas than common sense did not lead to our first million as originally projected," though two good ideas sprang from their partnership: Tunes for the Dunes, a project that sent 1,000 cassettes of new American music to soldiers serving in the Gulf, and "Club Hell," a play produced at Pace University in 1997. Fracchia is now Assistant Director/Recruiting Coordinator at Ithaca College's Career Development Center and Forrestal is an emergency room physician in Philadelphia.

1990: Margaret Butler has recently accepted a tenure-track position as assistant professor of Musicology at the University of Alabama.  She earned an M.A. in 1994 and a Ph.D. in 2000 from Ohio State University.  She conducted dissertation research in Turin, Italy as a Fulbright fellow and earned a Presidential Fellowship from the Graduate School at Ohio State. Her dissertation on eighteenth-century Italian opera won the distinguished dissertation award in Music from the Ohio State School of Music in 2000, and was subsequently published in Italy by the Istituto per i Beni Musicali in Piemonte in 2001. For the last year and a half, Butler has been associate director of the Center for West European Studies and European Union Center at the University of Pittsburgh.

1998: Tara Fox Hall is engaged to Eric Dietrich. She is an associate account manager for Modern Marketing Concepts in Endicott. Dietrich is Professor of Philosophy at Harpur College. The couple plans to marry in September.

1998: Charlene Theresa Cook and Michael Alan Meehl were married Oct. 5 in Johnson City, NY. Cook is a teacher for Bright Horizons, St. Louis, MO and her husband is a graduate student at Washington University. After a honeymoon in the Bahamas, the newlyweds reside in St. Louis, MO. (source: Press & Sun Bulletin)

1999: Lisa Cohen is pleased to anounce her engagement to John Dahlstrom. Cohen is a speech-language pathologist for Norwalk Hospital in Norwalk, CT. Dahlstrom is a computer programmer at Howard Hughes Medical Institute in New Haven, CT. They plan to marry in May 2004 in Yorktown Heights, NY.

1999: Amanda Pasquale and Jason Spellicy plan to tie the knot on June 14. Pasquale is regional director for U.S. Senator Charles Schumer in Binghamton. Spellicy is general manager of Uno Restaurant Inc. in Vestal. (source: Press & Sun Bulletin)

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